Model NO.: 111358-88-4
Product Name: Lestaurtinib
CAS No.: 111358-88-4
Mf: C26h21n3o4
MW: 439.469
Delivery by: DHL, TNT, FedEx, Hkems, UPS, etc
Export Markets: Global
Trademark: NEWBIO
Transport Package: Aluminum Foil Bags
Specification: SGS
Origin: China
HS Code: 0000000000
Model NO.: 111358-88-4
Product Name: Lestaurtinib
CAS No.: 111358-88-4
Mf: C26h21n3o4
MW: 439.469
Delivery by: DHL, TNT, FedEx, Hkems, UPS, etc
Export Markets: Global
Trademark: NEWBIO
Transport Package: Aluminum Foil Bags
Specification: SGS
Origin: China
HS Code: 0000000000
Chemical Information:Â
Product Name | Lestaurtinib |
Molecular Formula | C26H21N3O4 |
Molecular Weight | 439.469 |
Storage | Store at -20°C |
Stability |
3 years   - 20 ºC powder
6 months  -80 ºC dissolved in a solvent
|
Solubility | Soluble in DMSO >Â 10 mM |
General tips | For obtaining a higher solubility , please warm the tube at 37 ºC and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20ºC for several months. |
Shipping Condition |
Evaluation sample solution :Â ship with blue ice
All other available size: ship with RT , or blue ice upon request
|
Details:
Â
Synonyms:A 154475.0;(9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:321kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one;CEP 701;KT 5555;SP 924;(9S-(9α,10β,12α))-2,3,9,10,11,12-hexahydro-10-hydroxy-10-(hydroxyMethyl)-9-Methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one;SPM-924
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Description:Lestaurtinib (rINN, codenamed CEP-701) is a tyrosine kinase inhibitor structurally related to staurosporine. It was investigated by Cephalon as a treatment for various types of cancer. It is an inhibitor of the kinases FLT3,[1] JAK2,[2] TrkA, TrkB and TrkC.[3]
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Application:Â
Potent JAK2, FLT3 and TrkA inhibitor (IC50 values are 0.9, 3Â and <Â 25 nM respectively) that prevents STAT5 phosphorylation (IC50 =Â 20 -Â 30 nM). Exhibits antiproliferative activity in vitro (IC50 =Â 30 -Â 100 nM in HEL92.1.7 cells) and is effective against myeloproliferative disorders in vivo.
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Notification:This compound is used only for research and not for human trials!Â
Other Small Molecular API:
Â
AZD9291 | 1421373-65-0 |
E7080 | 417716-92-8 |
Afatinib diMaleate | 439081-18-2 |
XL184 S-MALATE | 1140909-48-3 |
Crizotinib | 877399-52-5 |
Axitinib | 319460-85-0 |
WZ4002 | 1213269-23-8 |
Vandetanib | 443913-73-3 |
Sunitinib | 557795-19-4 |
Regorafenib | 755037-03-7 |
Imatinib | 152459-95-5 |
Foretinib | 849217-64-7 |
trametinib | 871700-17-3 |
Tivozanib | 475108-18-0 |
Pelitinib | 257933-82-7 |
Cediranib | 288383-20-0 |
Selumetinib | 606143-52-6 |
Tozasertib | 639089-54-6 |
CapMatinib | 1029712-80-8 |
Amuvatinib | 850879-09-3 |
Lestaurtinib | 111358-88-4 |
Brivanib | 649735-46-6 |
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1.The parcels will be sent within 24 hours once the order is verified.
2.Packaging is fully in accordance with customer demand.
3.There will be discounts whether you are an old customer or not.
To your satisfiction, here are our advantages
1.High quality and competetive price
1)we can offer coa certificate and official invoice.
2)we are manufacturer with own lab and factory, can provide high quality products with factory price.
3)products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (sgs/ cti/ its), only after your confirmation will we send it out to you.
2.Fast and safe delivery
1)products can be sent out in 24 hours after payment.Tracking number available, fixed service person are 7x24h for you to contact.
2) secure and discreet shipment.Various transportation methods for your choice, like dhl/ups/tnt/fedex/sf-express.
3)customs pass and satisfied rate >99%.
4)for hot sale products we have stock in there for transferring.
3 we have clients throughout the world
1) professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility.
3) high quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.Â
Delivery:
Commitment:
Chemical Information:To your satisfiction, here are our advantages
1.High quality and competetive price
1)we can offer coa certificate and official invoice.
2)we are manufacturer with own lab and factory, can provide high quality products with factory price.
3)products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (sgs/ cti/ its), only after your confirmation will we send it out to you.
2.Fast and safe delivery
1)products can be sent out in 24 hours after payment.Tracking number available, fixed service person are 7x24h for you to contact.
2) secure and discreet shipment.Various transportation methods for your choice, like dhl/ups/tnt/fedex/sf-express.
3)customs pass and satisfied rate >99%.
4)for hot sale products we have stock in there for transferring.
3 we have clients throughout the world
1) professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility.
3) high quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.Â
Delivery:
1) Products can be sent out within 24 hours after payment.Â
2) Secure and discreet shipment.Â
3) Various methods for your choice, like DHL/TNT/FedEx/SF-express.
Commitment:
1. We are manufacturer with own factory and we sale this product at a best quality and low price.
2. This product is available in stock, please contact the sale for more details.
3. We have QA & QC department to guarantees the ex-factory product pass rate can reach 100%.Â
====================================================
2. This product is available in stock, please contact the sale for more details.
3. We have QA & QC department to guarantees the ex-factory product pass rate can reach 100%.Â
====================================================
Contactct:
Telephone: +86-027-87002705
Mobile:Â +86-13638641831 +86-13277093700
Â
Â
Â
Â
FaceBook:Â https://www.facebook.com/newbiopharma/
Website:Â Â http://www.newbiopharm.com/
Online Store:Â http://biocar.en.made-in-china.com/
©Wuhan Newbio Pharm-Tech Co., Ltd.
Newbio is a reliable supplier and looks for a long term business relationship!!!
Newbio is a reliable supplier and looks for a long term business relationship!!!
Â
Product Name | Lestaurtinib |
Molecular Formula | C26H21N3O4 |
Molecular Weight | 439.469 |
Storage | Store at -20°C |
Stability |
3 years   - 20 ºC powder
6 months  -80 ºC dissolved in a solvent
|
Solubility | Soluble in DMSO >Â 10 mM |
General tips | For obtaining a higher solubility , please warm the tube at 37 ºC and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20ºC for several months. |
Shipping Condition |
Evaluation sample solution :Â ship with blue ice
All other available size: ship with RT , or blue ice upon request
|
Details:
Â
Synonyms:A 154475.0;(9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:321kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one;CEP 701;KT 5555;SP 924;(9S-(9α,10β,12α))-2,3,9,10,11,12-hexahydro-10-hydroxy-10-(hydroxyMethyl)-9-Methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one;SPM-924
Â
Â
Description:Lestaurtinib (rINN, codenamed CEP-701) is a tyrosine kinase inhibitor structurally related to staurosporine. It was investigated by Cephalon as a treatment for various types of cancer. It is an inhibitor of the kinases FLT3,[1] JAK2,[2] TrkA, TrkB and TrkC.[3]
Â
Â
Application:Â
Potent JAK2, FLT3 and TrkA inhibitor (IC50 values are 0.9, 3Â and <Â 25 nM respectively) that prevents STAT5 phosphorylation (IC50 =Â 20 -Â 30 nM). Exhibits antiproliferative activity in vitro (IC50 =Â 30 -Â 100 nM in HEL92.1.7 cells) and is effective against myeloproliferative disorders in vivo.
Â
Â
Notification:This compound is used only for research and not for human trials!Â
Other Small Molecular API:
Â
AZD9291 | 1421373-65-0 |
E7080 | 417716-92-8 |
Afatinib diMaleate | 439081-18-2 |
XL184 S-MALATE | 1140909-48-3 |
Crizotinib | 877399-52-5 |
Axitinib | 319460-85-0 |
WZ4002 | 1213269-23-8 |
Vandetanib | 443913-73-3 |
Sunitinib | 557795-19-4 |
Regorafenib | 755037-03-7 |
Imatinib | 152459-95-5 |
Foretinib | 849217-64-7 |
trametinib | 871700-17-3 |
Tivozanib | 475108-18-0 |
Pelitinib | 257933-82-7 |
Cediranib | 288383-20-0 |
Selumetinib | 606143-52-6 |
Tozasertib | 639089-54-6 |
CapMatinib | 1029712-80-8 |
Amuvatinib | 850879-09-3 |
Lestaurtinib | 111358-88-4 |
Brivanib | 649735-46-6 |
Â
1.The parcels will be sent within 24 hours once the order is verified.
2.Packaging is fully in accordance with customer demand.
3.There will be discounts whether you are an old customer or not.
To your satisfiction, here are our advantages
1.High quality and competetive price
1)we can offer coa certificate and official invoice.
2)we are manufacturer with own lab and factory, can provide high quality products with factory price.
3)products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (sgs/ cti/ its), only after your confirmation will we send it out to you.
2.Fast and safe delivery
1)products can be sent out in 24 hours after payment.Tracking number available, fixed service person are 7x24h for you to contact.
2) secure and discreet shipment.Various transportation methods for your choice, like dhl/ups/tnt/fedex/sf-express.
3)customs pass and satisfied rate >99%.
4)for hot sale products we have stock in there for transferring.
3 we have clients throughout the world
1) professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility.
3) high quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.Â
Delivery:
Commitment:
To your satisfiction, here are our advantages
1.High quality and competetive price
1)we can offer coa certificate and official invoice.
2)we are manufacturer with own lab and factory, can provide high quality products with factory price.
3)products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (sgs/ cti/ its), only after your confirmation will we send it out to you.
2.Fast and safe delivery
1)products can be sent out in 24 hours after payment.Tracking number available, fixed service person are 7x24h for you to contact.
2) secure and discreet shipment.Various transportation methods for your choice, like dhl/ups/tnt/fedex/sf-express.
3)customs pass and satisfied rate >99%.
4)for hot sale products we have stock in there for transferring.
3 we have clients throughout the world
1) professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility.
3) high quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.Â
Delivery:
1) Products can be sent out within 24 hours after payment.Â
2) Secure and discreet shipment.Â
3) Various methods for your choice, like DHL/TNT/FedEx/SF-express.
Commitment:
1. We are manufacturer with own factory and we sale this product at a best quality and low price.
2. This product is available in stock, please contact the sale for more details.
3. We have QA & QC department to guarantees the ex-factory product pass rate can reach 100%.Â
====================================================
2. This product is available in stock, please contact the sale for more details.
3. We have QA & QC department to guarantees the ex-factory product pass rate can reach 100%.Â
====================================================
Contactct:
Telephone: +86-027-87002705
Mobile:Â +86-13638641831 +86-13277093700
Â
Â
Â
Â
FaceBook:Â https://www.facebook.com/newbiopharma/
Website:Â Â http://www.newbiopharm.com/
Online Store:Â http://biocar.en.made-in-china.com/
©Wuhan Newbio Pharm-Tech Co., Ltd.
Newbio is a reliable supplier and looks for a long term business relationship!!!
Newbio is a reliable supplier and looks for a long term business relationship!!!
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