DNA sequencing can show the explosive growth of disease-prone genetic information

Release date: 2015-01-22

At present, one-third of the world economy is driven by biotechnology, and biotechnology is playing an increasingly important role in medicine and agriculture. It can be said that the whole world is developing around DNA.

As genetic technology continues to advance, the cost of acquiring and interpreting DNA sequences will be lower and lower. It is expected that by 2020, the sequencing of the human genome will become as easy as flushing the toilet. Ordinary people use biotechnology to improve their quality of life, which is as common as today's computer programming or online shopping.

Not only that, but after unlocking the disease, the human genome sequence, and repairing DNA, human life will soon be extended, and it is expected to double in 2050.

Of course, the exploration of genes may also face various risks.

DNA sequencing can show disease trends

Now, when people are sick, they think of going to the hospital to prescribe drugs, but if everyone knows their personal genomic information from birth, then the predictive drug model will be opened in the future.

Genome monitoring can help people predict from genetic diseases to rare diseases and even cancer, and it can also help doctors to personalize medications for patients. Even if you don't have to wait until birth, you can get all kinds of genetic information of the baby by detecting the mother's peripheral blood.

For example, smear a medium and send the sample to a gene sequencing company for big data analysis. Soon, you can see your own sequencing results on the Internet, such as potential diseases, your own genetic background, health index, etc. Some private and interesting information.

In fact, some diseases do not seem to prevent it. This is not the case. When you get your own sequencing results, but know that you may have a disease in the future, you can use the doctor's advice for early prevention, such as vitamin supplementation, UV exposure, no smoking.

Sequencing costs continue to decline

It should be pointed out that DNA can be seen from its double helix structure is complicated, it is conceivable that the sequencing process is also very difficult and expensive. But what is certain is that as technology continues to advance, this cost will continue to decline.

In 2005, the marginal cost of completing a DNA sequencing was about $3 billion. In 2007, it fell to $1 million. In 2013, it continued to drop to $25,000. Until 2014, the cost of sequencing human genomes has dropped to 1,000. Dollar.

Undoubtedly, the cost of sequencing will be lower and lower. It may be that by 2016, completing a sequencing is equivalent to buying pizza, and by 2020, the cost of sequencing is cheaper than flushing a toilet.

In fact, the bottleneck that now blocks the further spread of biotechnology is not biotechnology itself, but information science. Interpretation and cracking after gene sequencing requires enormous computing power.

At present, the analytical power of computers has doubled in two years, and the price of sequencing has declined by 5-10 times per year. It is believed that the days when most people can bear the cost of sequencing human genomes are not far away.

Sequencing companies welcome opportunities

Gene sequencing is based on value-added services for charging a genome, two genomes, a part of a gene, or just a single gene scan, which is charged at the current market price.

It is foreseeable that the rate of decline in gene sequencing costs is slowly easing. The new company is trying to get involved and become a new member of the gene sequencing family, offering cheaper services to everyone. So, now is the best time for gene sequencing companies.

For us, this also means that the future medical treatment is no longer passive. It is no longer to see problems in the body and then to “correct”. Instead, it can make a preliminary prediction and prevent it before the disease occurs, thus ensuring that the disease is not Will happen, or make the worst preparations.

A company has a product that helps people see what cancer they are. They provide a service to patients, that is, they can capture information through a test, making the drug more effective. Doctors only need to draw a tick to get this. Interpretation. Instead of focusing on sequencing, the company writes reports based on computer data. This is a very complex database, but they can interpret cancer-related information based on this database.

Another thing we think will be achieved is that gene sequencing will end the painful examinations such as mammography and colonoscopy. In 2020, only the blood can be collected to know the results of the above tests, and there will be newer technologies and equipment. Genetic testing.

What's more interesting is that perhaps in 2020, when you took a small machine and swayed in front of everyone, "I need to find a love now. I hope he is healthy, beautiful, kind, and good for children." You can guide you through the crowd until you find someone you like.

We may use genes to find a lover or choose a career direction. Biotechnology may become another basic technology that cannot be separated from human beings after water, electricity, coal computers and networks. Even when you want a solid wood bookcase, go to the gene store, select a suitable genetic sequence, add it to your shopping cart, and then get a tree trunk that grows into a square.

This series of technological innovations will bring more opportunities for related companies to bring more products to market.

Source: Chinese Journal of Science

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