Munich, Germany, University student transformation Ultimaker medical 3D printing human tissue

Students at the Technical University of Munich in Germany have recently modified the Ultimaker 2+ 3D printer and developed a bio-ink called 3D printing called “biotINK” to participate in this year's biology competition – the iGEM Challenge Competition.

3D bioprinting is one of the most exciting areas of research today. Using special 3D printers, experts have been able to create precisely shaped human tissue using real human cells, and these 3D printed tissues may soon be used for transplantation and other purposes. However, the 3D printing organization requires additional special substances, because the cells themselves do not have 3D printing characteristics, and they cannot be directly extruded from the nozzles of the 3D printer. So, scientists developed bio-ink, which mixes bio-ink and cells so that cells can be printed into tissue.

A group of students from the Technical University of Munich in Germany took their own bio-ink for 3D bio-printing and participated in the iGEM Challenge Competition, a 3D bioprinting competition for biologists, biochemistry and bioengineers every year. Their bio-ink contains biotin and streptomycin, and the team named it "biotINK."

Researchers believe that their bio-inks can be seamlessly integrated with other 3D bio-printing technologies that require temporary support to support organic structures. biotINK functions like a "molecular superglue" that combines biotin and receptors to enable scientists to pinpoint 3D printed cells, allowing "three-dimensional intercellular communication and physiological microenvironment" to form faster.

"Streptomycin binds to biotin and cross-links to form a network structure, making it possible for biotin to bind to receptors," said research group member Luisa Krumwiede. "They then polymerize to form a three-dimensional structure."

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Xi'an Tian Guangyuan Biotech Co., Ltd. , https://www.tgybiotech.com