A new generation of targeted drugs in China approved lung cancer patients to usher in new hope
March 09, 2017 Source: China News Network
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Boehringer Ingelheim China headquarters announced in Shanghai on the 27th that the second-generation EGFR-targeted drug, afatinib, has been approved in China, bringing new hope to lung cancer patients in China.
Lung cancer is one of the most common malignant tumors in China. About 600,000 new lung cancer patients are added each year, which is the leading cause of cancer death. With advances in the treatment of lung cancer, it has been found that for lung cancer patients with certain genetic mutations, targeted therapy will benefit patients more than chemotherapy. In China, the most common type of genetic mutation in patients with non-small cell lung cancer is the EGFR gene mutation, which accounts for about 50%. For this group of patients, the selection of targeted drugs for EGFR is the most ideal treatment.
Currently, lung cancer can be roughly classified into non-small cell lung cancer and small cell lung cancer, and non-small cell lung cancer accounts for 80-85% of all lung cancers. For patients with early stage lung cancer, comprehensive treatment methods including surgery are often used. For patients with advanced non-small cell lung cancer, chemotherapy is the main method. However, since chemotherapy acts on normal cells as well as cancer cells, it inevitably brings about more side effects and increases the suffering of patients. With the continuous advancement of precision medicine for lung cancer, lung cancer has been found to have some special genetic changes. For different types of genetic mutations in lung cancer patients, the corresponding targeted drugs can be selected. Because targeted drugs only act on specific cancer cells, they are more effective and safer than chemotherapy.
It is reported that the drug is approved for the treatment of lung cancer patients with positive EGFR mutations, and is also approved for patients with locally advanced or metastatic squamous non-small cell lung cancer during or after chemotherapy with platinum.
Prior to approval in China, afatinib was approved in more than 70 countries for the treatment of patients with EGFR mutation-positive non-small cell lung cancer and became the first choice for EGFR-targeted drugs in several countries.
Ginger is the rhizome of the plant Zingiber officinale, consumed whole as a delicacy, medicine, or spice. It is the underground stem of the ginger plant. The ginger plant has a long history of cultivation, having originated in Asia and is grown in India Southeast Asia, West Africa and the Caribbean. The actual name for ginger is Root Ginger. However, it is commonly referred to as ginger, as the meaning is well known. It is used for abdominal bloating, coughing, vomiting, diarrhea, and rheumatism. The most active chemical compounds in ginger are known as the gingerols, which are also the most aromatic compounds in this root. Ginger also contains shogaols, which are formed during the drying process.
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