Application of new method for space sterilization in SPF animal laboratory

【Abstract】Laboratory animals: artificially cultivated to control the microorganisms and parasites carried by them; the genetic background is clear, the source is clear; used in scientific experiments, production and verification of drugs, biological products and other sciences Experimental animals. SPF-class animals (Grade 3): Also known as pathogen-free animals, except for the pathogens that should be excluded from primary and secondary animals, do not carry major potential infections or pathogens that interfere with scientific research. Although the state has a standard for its biosafety level, the biosafety laboratory's protective facilities are standardized, and the barrier system is used to raise specific pathogen-free (SPF)-level experimental animals, while the isolation system is suitable for feeding SPF and sterile (GF) grades. In order to ensure the normal growth of experimental animals, experimental animals need to strictly adjust the temperature and humidity according to the regulations, provide fresh air, and eliminate harmful gases, pathogenic microorganisms and dust particles, but it is also inevitable that there will be a risk of air circulation dead spots and microbial contamination. Therefore, effective measures must be taken to kill space microbes. And what sterilization method can effectively prevent microbial contamination without affecting the safe and healthy growth of experimental animals?
[Keywords] SPF animal laboratory, SPF animal, space sterilization, animal laboratory sterilization

Orphem Space Dry Mist Sterilization System is imported from Europe and France. It is designed for the new GMP. The dry mist sterilization system and space sporicide can meet the requirements of disinfection and sterilization in clean areas. It meets the requirements of the new GMP and is easy to pass. 3 - The atomization effect of 5 micron particles. Orpheum's unique and special structural design makes it possible to integrate the compression, ventur spray and internal and external spattering of the droplets in the case of inputting only electric energy, so that the special liquid sporicide becomes a dry mist state. The tiny particles are sprayed out, which expands the efficiency of the large dry mist equipment, greatly reduces the space occupation, and solves the problems of heat dissipation and noise reduction.

The domestic hydrogen peroxide dry mist sterilization system mixes hydrogen peroxide and peracetic acid, and consists of a separate sterilization system consisting of a compressed air pipe and a stainless steel atomizing nozzle and a spray can equipped with a disinfectant. The atomized particles have an average diameter of 7.5 μm, and the nozzle is sprayed from the center to the periphery. The weak initial kinetic energy is an important factor affecting the diffusibility. The strong oxidizing properties of peracetic acid also greatly enhance the corrosiveness of the surface of the device, and generally cause rust, foaming and the like.

[Oufeimu dry fog sterilization system features]

1, the sterilization effect is good, there is a kill rate of 6 logarithmic values ​​for the black

2, a broad spectrum of bactericidal ability, can kill more than 200 kinds of microorganisms including spores, molds and viruses

3, 5um dry fog particles, very good diffusion can spread to every corner, do Brownian motion in the air

4, stable performance, not affected by temperature, PH

5, colorless, non-toxic, no residue, safe and reliable

6, the verification information is complete, easy to pass GMP verification

7, sterilization time is very short, 2-3 hours can complete the entire sterilization process

8, imported to Europe, designed for disinfection of clean areas, fully in line with GMP requirements

9, small size, easy to operate, flexible movement to meet different space needs

10, cost-effective, saving disinfection costs

[Oufim dry fog sterilization system parameters]

Spray particle size: average 3-5um

Kinetic energy: power supply

Injection speed: 90m / sec

Injection volume: 1000ml / hour

With sporicide dosage: 1000ml

Applicable liquid: Norfolk high purity stable hydrogen peroxide sporicide (dry fog is hydrogen peroxide)

Power: 1.1 kW

Sterilization volume: 50-1000 cubic meters

Material: HDPE

Size: 50cm × 33cm × 34cm (length × width × height)

Net weight: 5.8kg

Comparison table of Orphem hydrogen peroxide dry mist sterilization system and domestic hydrogen peroxide dry fog system

Laboratory animal facility technical indicators

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