According to the British "Independent" reported on the 1st, Danish scientists have developed a bioengineered ovary - an ovarian scaffold stripped of DNA and living cell components, which is the world's first fertilization that allows immature egg cells to develop into a suitable transplant. The artificial ovary of the cell. The researchers say that this artificial ovary is expected to make women who have undergone cancer chemotherapy risk-free to become mothers in the future.

Some women who need emergency medical treatment will preserve ovarian tissue (containing thousands of immature eggs, which are found in fluid-filled sacs called follicles), hoping to implant ovarian tissue after treatment. in vivo. However, if cancer cells remain in the ovarian tissue, the risk of cancer from re-transplantation will be high.

The latest technology from the Copenhagen Institute of Technology team avoids this risk. They use a chemical process that removes DNA from ovarian tissue cells and may contain other features that cause false control of cell growth, and then implants immature egg cells into this empty ovarian scaffold.

The results showed that immature eggs and tissue scaffolds could be reintegrated, survived in this scaffold, and then transplanted into a living host, a mouse.

Team leader Susanna Bols said: "This is the first time that isolated human follicles have survived in decellularized human scaffolds. Experiments have shown that it can provide a new maternity protection strategy without the risk of malignant cells returning. ."

Previously, British scientists first removed immature cells from follicles and cultured them into mature eggs in vitro, but this study did not have ovarian scaffolds that allowed follicles to re-implant and develop naturally.

Independent doctors believe that this is a "groundbreaking" study, "is an extremely important advancement in the field of maternity protection." But this process still needs to be streamlined and proven to be safe for humans, which can take years. Dr. Stewart Ravi, a gynaecologist at Hammersmith Hospital in the United Kingdom, said: "If this technique proves to be effective, it will have an advantage over in vitro fertilization (IVF) and frozen eggs."

The researchers presented the results at the annual meeting of the European Society for Human Reproduction and Embryology (ESHRE) in Barcelona on Monday. (Reporter Liu Xia)


Neonatal Phototherapy Eye Mask

Neonatal Phototherapy Eye Mask,Phototherapy Eye Mask,Baby Eye Therapy Mask,Newborn Eye Mask

Wenzhou Celecare Medical Instruments Co.,Ltd , https://www.celecaremed.com