Effect of Sophora flavescens
Sophora flavescens, matrine, matrine flavonoids and other anti-arrhythmia effects. Sophora flavescens can increase coronary flow, protect myocardial ischemia and reduce blood lipids, total alkaloids can also prevent leukopenia and radiation resistance. Alcohol extracts have a killing effect against vaginal trichomoniasis and amoeba protozoa. The decoction has inhibitory effects on Mycobacterium tuberculosis, Shigella, Staphylococcus aureus, and Escherichia coli, and also has inhibitory effects on various dermatophytes. And diuretic, anti-inflammatory, anti-allergic, analgesic and asthma, expectorant effect.
1. Treatment of acute fever with intramuscular injection of 20% to 3ml of 50% Kushen injection. 2 times a day. Treatment of acute tonsillitis, acute conjunctivitis, acute mastitis, periodontitis, acute tracheitis, acute pyelonephritis, surgical infection 220 cases of fever caused by blisters and other diseases, with an effective rate of 90%, a cure rate of 74%. 〖Chinese Journal of Integrated Traditional and Western Medicine, 1985;(2): 108〗
2. Insomnia Treatment a. Sophora flavescens 500g, add cold water 1000ml, soak for 12-20 hours, fry for 1 hour, take juice 400-600ml, add water 1000ml, decoct 300-500ml, add water 1000ml, decoct 500ml. The 3 decoctions were mixed and concentrated to 1 000ml. Sugar was added. Adults were 20ml each time, children were 5-15ml each time, once a day orally. 101 cases were treated, 51 cases were effective, 31 cases were markedly effective, and 14 cases were good effect. , Ineffective in 5 cases, The effective rate is 95%. 〖Chinese Herbal Medicine 1979; (2): 38〗 b. Sophora flavescens 30 grams, Suanzaoren 20 grams, add water 100ml, thick fry to 15 ~ 20ml, 20 minutes before bed every night Chongfu, 10 to 15 days for a course of treatment. Treatment of 20 cases, cured in 6 cases, markedly effective in 7 cases, improved in 7 cases. 〖Zhejiang Traditional Chinese Medicine 1984;(10): 440〗
3. Treatment of epilepsy with purple ginseng tablets: Sophora flavescens with purple gold ingot (Gledigno mushroom 60g, Chinese gallnut 60g, continuous sequel 30g, medlar 45g, cinnabar 22.5g, lumbar yellow 22.5g, musk 9g), according to 1:4 dose Proportion, co-pulverizing, made into tablets, 0.3g per tablet. Oral. Treatment of 40 cases, 17 cases cured, 13 cases effective, the total effective rate was 75%. After the control observation, after the addition of Sophora flavescens later than the single use of gold ingot Good effect. 〖Chinese Journal of Traditional Chinese Medicine 1983;(1): 48〗
4. Treatment of cardiac arrhythmias a. Sophora flavescens 30g, Salvia miltiorrhiza 30g, Codonopsis pilosula 30g, Zhigancao 15g, Boziren 10g, Changshan 10g, 1 dose per day, 2 doses of decoction, 30 days for 1 course of treatment. Other anti-arrhythmic drugs. Treatment of premature beats in 35 cases, markedly improved in 12 cases, progressed in 16 cases, ineffective in 7 cases. 〖Fujian Chinese Medicine 1983; (6): 26〗 b. Sophora flavescens 10 ~ 30g, deer grazing grass 10 ~ 15g, Zhigancao 10 ~ 15g as the basic side. Decoction, day service 1, 30 to 60 days for a course of treatment. Treatment of premature beats in the main arrhythmia in 72 cases, markedly (electrocardiogram premature beat disappeared, no recurrence ) 42 cases, improved in 15 cases, invalid in 15 cases. 〖Tianjin Pharmaceutical 1980; (7): 432〗 c. Sophora flavescens decoction 3 times, combined decoction, concentrated, plus a single syrup seasoning, per 100ml containing bitter herbs 30g. Each time 50ml, 2 times a day, and even served for 2 to 4 weeks. Treatment of 32 cases of frequent ventricular premature beats, the total effective rate of 90.6%, stable efficacy. 〖Jun Pharmacy 1978; (7): 41 〗 d. Sophora flavescens tablets (each containing 2g crude drug), 3 to 10 tablets each time, 3 times a day, the average course of treatment is 11 weeks. 167 cases of rapid arrhythmia treatment, the effective rate of premature contraction is 62%, ( Premature ventricular premature beats are 59.5%. Premature to 80.8%), good efficacy against premature beat to infections and fatigue caused 〖new journal Medicine 1977; (7): 24〗.
5. Treatment of leukopenia caused by radiotherapy Intramuscular injection of matrine, usually 200mg (12ml) first, then increased to 400mg. Treatment of malignant tumors after leukopenia in 25 cases, 21 cases of leukocytes rise, the remaining 4 cases of white blood cells did not Did not fall, have completed radiotherapy. 〖Tianjin Pharmaceutical 1979; (4): 154〗
6 treatment of esophagitis flavescens 30g, Coptis 10g, rhubarb 6g. Add 150ml water to fry 60ml, 20ml orally every time, 3 times a day. Fasting 1 hour after taking the drug. Treatment of 10 cases, all disappeared within 7 days. Of which 6 After 10 days of medication, gastroscopy, 5 cases of esophageal mucosa basically returned to normal. 〖 Gansu Journal of Traditional Chinese Medicine 1992;(1): 42〗
7. Treatment of Hepatitis, Sophora flavescens, Artemisia capillaris, 10g each, Gentiana, Alisma, 15g, Shuijianbi. Treating 30 cases of acute jaundice hepatitis, cured 23 cases, markedly effective in 5 cases, total effective rate 93.3%. 〖Zhejiang Traditional Chinese Medicine 1987 ;(12): 533〗
8. Treatment of trichomoniasis enteritis purslane 25 ~ 30g (fresh products 150 ~ 250g), flat storage, flavescens each 25 ~ 40g, decoction 2 times morning and evening fasting warm clothes. Treatment of 16 cases, clinical cure in 15 cases, Interrupted treatment in 1 case. 〖Chinese Journal of Traditional Chinese Medicine 1991;(12): 46〗
9. The treatment of fungal enteritis flavescens powder 2g, Yunnanbaiyao 1g, mixing orally, sooner or later each time; or according to the above ratio of pills taken orally. 30 days for a course of treatment. Treatment of 40 cases, the results of recovery in 28 cases, improved 12 Example. 〖Chinese Journal of Traditional Chinese Medicine 1983;(6): 57〗
10. Treatment of schistosomiasis ascites every day with Sophora 6 ~ 8g decoction. Treatment of 25 cases, mostly in the 2nd day after taking the drug more urine, abdominal circumference decreased, creating conditions for splenectomy. 〖Jiangsu Journal of Traditional Chinese Medicine 1959; (8): 8〗
1. Treatment of Giardia lamblia. a. Tablets or syrups made from Sophora flavescens extract, adult 30g (crude drug) daily, divided into 3 doses orally, reduced by children, and used for 7 days for 1 course of treatment. In 100 cases, 92 cases were cured. Most of the symptoms disappeared on the 1st to the 4th day after treatment. The stools returned to normal and the feces turned negative. Some cases were followed up for 3 to 9 months. Except 1 exception, no recurrence was observed. 〖Chinese Journal of Internal Medicine 1965;13(7): 614〗 b. Retention enema with 25% flavescens decoction, 100-200ml each time for adults, once daily for 5 consecutive days, 61 cases treated, 53 cases cured, 3 cases improved, total Effectiveness is 92%. A small number of cases feel nausea after taking the medicine, and individual fingers are numb, but they do not affect continuing treatment. 〖Chinese Journal of Internal Medicine 1964;12(9): 874
2. Treatment of pear flagellate disease, bitter ginseng seeds, wolfberry 100 grams of each 6g, licorice 1.5g, Shuijianbi, day 1. 3 to 6 days for a course of treatment. Treatment of 15 cases, are more. 〖Fujian Chinese Medicine 1984;(4): 14〗
3. Treatment of tsutsugamushi disease matrine 200g, one hundred 150g, Chuanjiao 60g, alum 10g. Add water 500ml, boil for 20 to 30 minutes, to slag filtration, 40ml per night before going to bed with the enema, children reduce it. Treatment of 50 cases, Medication 2 to 4 times, all recovered. 〖Hubei Journal of Traditional Chinese Medicine 1981;(3): 37〗
4. Treatment of skin diseases a. 100% matrine injection intramuscularly, 2~4ml each time, once daily; or Sophora flavescens tablets, 5 tablets each time (each containing 0.3g of crude drug) orally, 3 times a day Treatment of acute, subacute eczema, seborrheic eczema dermatitis, genital eczema, generalized neurodermatitis and other 148 cases, the effective rate was 79%. 〖Chinese Herbal Medicine 1976; (1): 35〗 b. Sophora flavescens 30 ~ 60g, angelica 10g, paeonol 10g, suede 15g, raw atractylodes macrocephala 10g, raw barley 15g, rhizoma imperata root 20g, forsythia 15g, raw licorice 6g. Shuijianbi, daily one. Treatment of damp heat type urticaria and drug eruption 20 Cases, cured 19 cases, invalid 1 case. General medication 2 to 6 days that have a curative effect, 3 to 14 days can be cured. 〖Chinese Traditional Medicine 1983; (3): 41〗 c. Sophora flavescens 30g, Spotted 4g, realgar, Each of 6g of patina and borneol was used for researching fines, plus 75% alcohol 500ml, sealed for 7 days. The affected area was used 2 to 3 times a day. 21 cases of neurodermatitis were treated with satisfactory results. 〖Henan Traditional Chinese Medicine 1983; (3 ): 19〗 d. Sophora flavescens 60g, Hebi, Kochia scoparia 30g, White Peel, Cnidium each 40g, Dafengzi, Rhubarb each 20g, Honeycomb, raw almonds, alum, Phellodendron each 15g. Jianshui 1 000～2 000ml, washing outside Department, once daily, 1 hour each time, each dose can be used 3 to 4 times. After washing, avoid wind. If necessary, can continue to use 1 agent. Treat 68 cases of pruritic dermatosis, 48 ​​cases cured, 10 cases markedly improved, 6 cases improved , Invalid in 4 cases. 〖Shandong Traditional Chinese Medicine 1984;(3): 51〗 e. Sophora flavescens 200g, soaked in 500ml of mature vinegar for 5 days. Standby. Wash the affected area with warm water first, then use a cotton swab to disperse the liquid. Daily morning and evening 1 time. General medication 3 to 5 days effective. Treatment of neurodermatitis in 52 cases, cured in 45 cases, Significant progress in 7 cases. No adverse reactions. 〖Hubei Journal of Traditional Chinese Medicine 1985; (6): 20〗 f. 30g each of Senate and Hundred, 20g of Phellodendron amurense, add 50% alcohol to all submerged medicine, seal it for 1 day and use it. Wash the affected area with warm water before use, dry the water with a clean towel, and then use sterile cotton. The ball sting liquid rubbed the affected area, 2 or 3 times a day, on the 3rd is a course of treatment. In the treatment of 32 cases of acne, 31 cases were cured, 1 case was improved. 〖Shaanxi TCM 1990; 11(9): 419〗 g. Crude 50g, fresh cash 100g, 75% alcohol 500ml, sealed and immersed for 3 days and nights, decanted the supernatant, and then pressed the residue, and the secondary extraction was combined, filtered with fine gauze, bottling and set aside. Drugs, 3 to 5 times a day. Treatment of 51 cases of snoring, cured 44 cases, follow-up a year later, 3 cases of recurrence. Course of treatment for up to 30 days, the shortest 5 days, an average of 14 days. 〖Zhejiang Traditional Chinese Medicine 1991; 26 ( 6): 270〗 5. Treatment of scald flavescens 60g, Forsythia 20g. A total of research and go-between, through 80 mesh sieve, remove slag with sesame oil 200g and mix thoroughly. The affected area is washed with cold water, dried and coated, 2 times a day Treatment of 36 cases of I, II degree burns in small and medium-sized areas, except for 12 cases of the original use of Sijiqing treatment, after the scabs subgermination pharyngeal, replaced with the drug treatment, the remaining 24 cases were cured within 10 days. 1983;(7): 31
6. Treatment of Trichomonas vaginitis with Sophora flavescens 0.5g mixed with equal amounts of glucose, boric acid powder and alum powder as 1 dose for topical treatment. When used first, 1/5000 potassium permanganate solution was used to irrigate the vagina. After drying, sprinkle the powder. Once a day, 3 times for a course of treatment. Clinical observation of 176 cases, the total success rate was 71.5%. Among them, the disappearance of symptoms after 3 months, vaginal secretions without trichomoniasis are effective, accounting for 45.4 %. Chinese Journal of Obstetrics and Gynecology 1958;6(6): 544
7. Treatment of cervical erosion flavescens, keel, gentian, cork all equal parts, research and fine autoclaving, or loading capsules. Use can be powder or capsule into the vagina, once every other day, 6 times for a course of treatment. Treatment of 234 cases, recovery of 224 cases. 〖Bare foot doctor magazine 1976; (10): 17〗
8. For the treatment of gonorrhea, Sophora flavescens and Phellodendron each 50g, add water 1500ml, soak for 10 to 15 minutes, grind for 45 minutes, filter and concentrate to 500ml (make 10ml of crude drug in 100ml). Take 1 dose 3 times a day, and even serve 7 to 10 days. Treatment of 93 cases, cured 69 cases, invalid 24 cases. Italian imports of spectinomycin treatment group 93 cases, cured 60 cases, invalid 33 cases. 〖Chinese Journal of Dermatology 1991;24 (5): 347〗
9. Treat chronic keratorrhynum flavescens 30g, Kochia scoparia 30g, Chuanxiongpi 10g, Cnidium 10g, white peony 15g. 1 day, boil for about 10 minutes in a casserole, remove the dregs after leaving the fire. Warm, immersed lip in the liquid, every 15 minutes. Treatment of 20 cases, 17 cases were cured, markedly effective in 3 cases. The average course of treatment was 17 days. 〖Chinese Medicine Magazine 1980; (6): 32〗
10. For the treatment of acute tonsillitis, intramuscular injection of 50% matrine injection, 2 to 3 ml each time, 2 times a day, treatment of acute tonsillitis, acute conjunctivitis, acute mastitis, periodontitis, surgical infections More than 10 kinds of acute inflammatory diseases such as bloated, pyelonephritis, acute bronchitis, acute lymphadenitis and other 220 cases, the average effective in more than 90%, the cure rate in more than 74%. 〖Bare foot doctor magazine 1971; (6): 15〗
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