Release date: 2013-06-18
This hydrogel consists of a polymer with both positive and negative charges, which deflects the protein adhering to its surface and prevents the formation of collagen walls, thus completely resisting the body's natural attack response to foreign bodies.
Usually, after a patient receives a medical implant for a few days, the body will attack the implant (such as a prosthetic valve or device) due to rejection, thereby increasing the complexity of the damaged system. Even the most advanced medical equipment, when the organization appears foreign objects, it will also cause an attack on the human immune response.
The Shaoyi Jiang research group at the University of Washington has become a flexible biomedical material, hydrogel, which swells when exposed to water. The hydrogel consists of a polymer with both positive and negative charges, which deflects proteins adhering to its surface (protein surface condensation is the initial feature of collagen wall formation) and prevents the formation of collagen walls. Completely resists the body's natural attack response to foreign objects. Medical devices such as prosthetic heart valves, prostheses, etc. can be coated with this polymer coating to prevent rejection of the human body.
Source: Chinese Journal of Science
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